Zonisamide for Weight Reduction in Obese Adults

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منابع مشابه

Zonisamide for weight reduction in obese adults: a 1-year randomized controlled trial.

BACKGROUND Obese individuals who have failed to achieve adequate weight loss with lifestyle changes have limited nonsurgical therapeutic options. We evaluated the efficacy and tolerability of zonisamide, an antiepileptic drug, for enhancing weight loss in obese patients receiving diet and lifestyle guidance. METHODS This was a 1-year, randomized, double-blind, placebo-controlled trial conduct...

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Zonisamide for weight loss in obese adults: a randomized controlled trial.

CONTEXT Zonisamide is a marketed antiepileptic drug that has serotonergic and dopaminergic activity in addition to blockade of sodium and calcium channels. Weight loss was an adverse effect associated with zonisamide treatment in epilepsy clinical trials. OBJECTIVE To evaluate the efficacy of zonisamide for weight loss in obese adults. DESIGN AND SETTING Sixteen-week randomized, double-blin...

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Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study.

OBJECTIVE Zonisamide and bupropion have been investigated for weight reduction in obese adults. We conducted a preliminary study comparing the effect on body weight of the combination of these 2 drugs versus zonisamide monotherapy. METHOD This was a 12-week, randomized, open-label, parallel-group comparison of 2 active interventions conducted from October 2003 to June 2004. Eighteen obese wom...

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Auricular Acupressure for Weight Reduction in Obese Asian Young Adults: A Randomized Controlled Trial

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Gut Microbiota Composition in Obese and Normal Weight Adults in Iran

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 2012

ISSN: 0003-9926

DOI: 10.1001/2013.jamainternmed.99